Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 15/20 | 0.81 |
| ▸ | DRD2 | P14416 | 8/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.73 |
| ▸ | RECQL | P46063 | 4/20 | 0.73 |
| ▸ | BLM | P54132 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.73 |
| ▸ | THPO | P40225 | 3/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | KDM1A | O60341 | 1/20 | 0.73 |
| ▸ | HTR1A | P08908 | 1/20 | 0.73 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11099172 | 0.99 | DRD1 (0.81) | DRD1DRD2KDM4ERECQLBLM | |
| SCHEMBL7318746 | 0.90 | DRD1 (1.00) | DRD1DRD2KDM4ERECQLBLM | |
| Bromide SCHEMBL11251616 | 0.88 | DRD1 (1.00) | DRD1DRD2KDM4ERECQLBLM | |
| SCHEMBL11541489 | 0.87 | DRD1 (0.72) | DRD1DRD2KDM4ERECQLBLM | |
| Bromide SCHEMBL11604921 | 0.86 | DRD1 (0.73) | DRD1DRD2KDM4ERECQLBLM | |
| Bromide SCHEMBL11122510 | 0.85 | DRD1 (0.71) | DRD1DRD2KDM4ERECQLBLM | |
| SCHEMBL10939180 | 0.84 | DRD1 (0.73) | DRD1DRD2KDM4ERECQLBLM | |
| Fenoldopam SCHEMBL41214 | 0.84 | DRD1 (1.00) | DRD1DRD2KDM4ERECQLBLM | |
| Fenoldopam SCHEMBL34250 | 0.84 | DRD1 (1.00) | DRD1DRD2KDM4ERECQLBLM | |
| Fenoldopam SCHEMBL1815791 | 0.84 | DRD1 (1.00) | DRD1DRD2KDM4ERECQLBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165372-A | 6-Carboxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds and use as dopaminergic agents | SMITHKLINE CORPORATION (US) | 1979-08-21 | — | — | US | disclosed |