Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 8/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545424 | 0.84 | PTGS1 (0.56) | PTGS1PTGS2TSHRLTA4HCYP1A2 | |
| SCHEMBL11546890 | 0.82 | PTGS1 (0.60) | PTGS1PTGS2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11544742 | 0.82 | PTGS1 (0.60) | PTGS1PTGS2ALDH1A1MAPK1 | |
| SCHEMBL9339335 | 0.78 | PTGS1 (0.50) | PTGS1PTGS2TSHRLTA4HALDH1A1 | |
| SCHEMBL9339338 | 0.78 | PTGS1 (0.58) | PTGS1PTGS2TSHRLTA4HALDH1A1 | |
| SCHEMBL4374807 | 0.78 | PTGS1 (0.50) | PTGS1PTGS2TSHRLTA4HCYP1A2 | |
| SCHEMBL22588398 | 0.78 | PTGS1 (0.50) | PTGS1PTGS2TSHRLTA4HALDH1A1 | |
| SCHEMBL11477740 | 0.77 | TDP1 (0.53) | PTGS1PTGS2DPP4ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL9853816 | 0.77 | PTGS1 (0.49) | PTGS1PTGS2TSHRLTA4HCYP1A2 | |
| SCHEMBL3790160 | 0.76 | DPP4 (0.62) | DPP4TSHRLTA4HCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179563-A | COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY (US) | 1979-12-18 | — | — | US | disclosed |