Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11590007 | 0.88 | CES1 (0.42) | CES1POLBLMNASRCPTPN1 | |
| SCHEMBL9346011 | 0.88 | CES1 (0.46) | CES1POLBLMNASRCKCNN4 | |
| SCHEMBL11546667 | 0.88 | CES1 (0.46) | CES1POLBLMNASRCPTPN1 | |
| SCHEMBL11543991 | 0.87 | CES1 (0.44) | CES1POLBLMNASRCPTPN1 | |
| SCHEMBL3267061 | 0.85 | CES1 (0.48) | CES1POLBLMNASRCMEN1 | |
| SCHEMBL11543398 | 0.85 | CES1 (0.40) | CES1POLBLMNASRCPTPN1 | |
| SCHEMBL11547240 | 0.84 | CES1 (0.42) | CES1CES2 | |
| SCHEMBL9341932 | 0.82 | CES1 (0.44) | CES1POLBLMNASRCPTPN1 | |
| SCHEMBL135045 | 0.80 | CES1 (0.54) | CES1LMNASRCKCNN4TSHR | |
| SCHEMBL11541964 | 0.79 | CES1 (0.34) | CES1PTPN1HPGDCES2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082821-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1978-04-04 | — | — | US | claimed |
| US-4160794-A | CURING OR POLYMERIZATION PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
| US-4082821-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |