Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.38 |
| ▸ | CASP5 | P51878 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589869 | 0.98 | CHRM5 (0.67) | CHRM5ADRA2CACHESMN1; SMN2OPRM1 | |
| SCHEMBL1586529 | 0.98 | CHRM5 (0.67) | CHRM5ADRA2CACHESMN1; SMN2OPRM1 | |
| SCHEMBL11545422 | 0.98 | CHRM5 (0.67) | CHRM5ADRA2CACHESMN1; SMN2OPRM1 | |
| Hydrochloric Acid SCHEMBL8191714 | 0.96 | CHRM5 (0.64) | CHRM5ADRA2CACHESMN1; SMN2OPRM1 | |
| Hydrochloric Acid SCHEMBL6590070 | 0.96 | CHRM5 (0.64) | CHRM5ADRA2CACHESMN1; SMN2OPRM1 | |
| Hydrochloric Acid SCHEMBL2674614 | 0.96 | CHRM5 (0.64) | CHRM5ADRA2CACHESMN1; SMN2OPRM1 | |
| Hydrochloric Acid SCHEMBL1604164 | 0.96 | CHRM5 (0.64) | CHRM5ADRA2CACHESMN1; SMN2OPRM1 | |
| SCHEMBL11546506 | 0.95 | CHRM5 (0.56) | CHRM5ADRA2CACHESMN1; SMN2OPRM1 | |
| SCHEMBL2673448 | 0.90 | CHRM5 (0.48) | CHRM5ADRA2CACHESMN1; SMN2GNAI3 | |
| SCHEMBL8100117 | 0.90 | CHRM5 (0.48) | CHRM5ADRA2CACHESMN1; SMN2GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163789-A | Anti-psychotic (cycloalkenylalkylpiperidino) benzamides | ANPHAR, S.A. (ES) | 1979-08-07 | — | — | US | disclosed |