Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544623 | 1.00 | KCNH2 (0.46) | KCNH2OPRM1OPRK1LTA4HOPRD1 | |
| SCHEMBL11548069 | 1.00 | KCNH2 (0.46) | KCNH2OPRM1OPRK1LTA4HOPRD1 | |
| SCHEMBL11491292 | 0.87 | KCNH2 (0.46) | KCNH2GRIN1SLC6A4SLC6A3 | |
| SCHEMBL11385476 | 0.87 | KCNH2 (0.46) | KCNH2GRIN1SLC6A4SLC6A3 | |
| SCHEMBL11385478 | 0.87 | KCNH2 (0.46) | KCNH2GRIN1SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL11393233 | 0.86 | KCNH2 (0.45) | KCNH2GRIN1SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL11393239 | 0.86 | KCNH2 (0.45) | KCNH2GRIN1SLC6A4SLC6A3 | |
| SCHEMBL11543221 | 0.85 | SLC6A4 (0.48) | KCNH2OPRM1OPRK1LTA4HOPRD1 | |
| SCHEMBL11545188 | 0.85 | SLC6A4 (0.48) | KCNH2OPRM1OPRK1LTA4HOPRD1 | |
| SCHEMBL11543215 | 0.85 | SLC6A4 (0.48) | KCNH2OPRM1OPRK1LTA4HOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179567-A | 2-Aryltropane compounds | STERLING DRUG INC. (US) | 1979-12-18 | — | — | US | disclosed |