Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542767 | 1.00 | MEN1 (0.40) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11542764 | 1.00 | MEN1 (0.40) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11545188 | 0.85 | SLC6A4 (0.48) | SLC6A3SLC6A4OPRK1KCNH2 | |
| SCHEMBL11543215 | 0.85 | SLC6A4 (0.48) | SLC6A3SLC6A4OPRK1KCNH2 | |
| SCHEMBL11543221 | 0.85 | SLC6A4 (0.48) | SLC6A3SLC6A4OPRK1KCNH2 | |
| SCHEMBL11546516 | 0.79 | SLC6A2 (0.64) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11546513 | 0.79 | SLC6A2 (0.64) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11383709 | 0.79 | SLC6A2 (0.64) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11392402 | 0.79 | SLC6A2 (0.64) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11392399 | 0.79 | SLC6A2 (0.64) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179567-A | 2-Aryltropane compounds | STERLING DRUG INC. (US) | 1979-12-18 | — | — | US | claimed |
| US-4179567-A | 2-Aryltropane compounds | STERLING DRUG INC. (US) | 1979-12-18 | — | — | US | disclosed |