Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536835 | 0.94 | HTT (0.44) | TDP1ALDH1A1L3MBTL1HTTMAPK1 | |
| SCHEMBL11540814 | 0.93 | TDP1 (0.53) | TDP1ALDH1A1L3MBTL1MAPK1MAPT | |
| SCHEMBL11535530 | 0.92 | TDP1 (0.53) | TDP1ALDH1A1L3MBTL1MAPK1MAPT | |
| SCHEMBL11534861 | 0.88 | SMN1; SMN2 (0.43) | TDP1ALDH1A1L3MBTL1HTTMAPK1 | |
| SCHEMBL11535116 | 0.88 | CYP1A2 (0.48) | ALDH1A1CYP1A2CYP3A4CYP2C19BLM | |
| SCHEMBL11534026 | 0.86 | SMN1; SMN2 (0.47) | TDP1ALDH1A1L3MBTL1HTTMAPK1 | |
| SCHEMBL11543545 | 0.85 | MAPT (0.43) | TDP1ALDH1A1L3MBTL1HTTMAPK1 | |
| SCHEMBL11534296 | 0.85 | SMN1; SMN2 (0.44) | TDP1ALDH1A1L3MBTL1HTTMAPK1 | |
| SCHEMBL11541610 | 0.84 | SMN1; SMN2 (0.41) | TDP1ALDH1A1L3MBTL1MAPK1MAPT | |
| SCHEMBL11536661 | 0.84 | PPARG (0.45) | L3MBTL1MAPTCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154842-A | Fungicidally and bactericidally active 1-azolyl-4-hydroxy-1-phenoxy-butane derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-15 | — | — | US | disclosed |