Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | CETP | P11597 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11588453 | 0.89 | CES1 (0.40) | PTPN1CES1LMNATSHRTDP1 | |
| SCHEMBL11542276 | 0.88 | CES1 (0.36) | PTPN1CES1LMNATSHR | |
| SCHEMBL9342068 | 0.88 | CES1 (0.39) | PTPN1CES1LMNAMEN1KMT2A | |
| SCHEMBL9346018 | 0.84 | CES1 (0.47) | PTPN1CES1LMNATSHR | |
| SCHEMBL11543056 | 0.81 | CES1 (0.38) | PTPN1CES1LMNAMEN1RAB9A | |
| SCHEMBL11540703 | 0.81 | CES1 (0.38) | PTPN1CES1LMNATSHR | |
| SCHEMBL11547246 | 0.80 | CES1 (0.43) | PTPN1CES1CETPLMNANAAA | |
| SCHEMBL11541968 | 0.75 | PRSS1 (0.34) | PTPN1CES1CETPCES2MEN1 | |
| SCHEMBL11171387 | 0.73 | CES1 (0.58) | CES1LMNANAAAL3MBTL1CES2 | |
| SCHEMBL2819529 | 0.72 | CES1 (0.45) | CES1LMNANAAAL3MBTL1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160794-A | CURING OR POLYMERIZATION PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
| US-4082821-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |