Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542597 | 0.96 | S1PR4 (0.41) | S1PR4SMN1; SMN2GLAHPGDMAPT | |
| SCHEMBL11542454 | 0.91 | S1PR4 (0.43) | S1PR4SMN1; SMN2GLAHPGDMAPT | |
| SCHEMBL11395938 | 0.87 | TTR (0.47) | S1PR4SMN1; SMN2HPGDMAPTTDP1 | |
| SCHEMBL11401738 | 0.87 | TTR (0.47) | S1PR4SMN1; SMN2HPGDMAPTTDP1 | |
| SCHEMBL8536773 | 0.77 | SMN1; SMN2 (0.41) | S1PR4SMN1; SMN2GLAMAPTTDP1 | |
| SCHEMBL11403559 | 0.77 | S1PR4 (0.43) | S1PR4SMN1; SMN2GLAHPGDMAPT | |
| SCHEMBL11401714 | 0.77 | S1PR4 (0.43) | S1PR4SMN1; SMN2GLAHPGDMAPT | |
| SCHEMBL8903264 | 0.76 | MAPT (0.60) | S1PR4SMN1; SMN2GLAHPGDMAPT | |
| SCHEMBL11398754 | 0.75 | S1PR4 (0.40) | S1PR4HPGDMAPTTDP1L3MBTL1 | |
| SCHEMBL11401119 | 0.74 | SMN1; SMN2 (0.62) | SMN1; SMN2HPGDMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171365-A | Antiviral aryloxyalkylpyrazoles | STERLING DRUG INC. (US) | 1979-10-16 | — | — | US | claimed |
| US-4171365-A | Antiviral aryloxyalkylpyrazoles | STERLING DRUG INC. (US) | 1979-10-16 | — | — | US | disclosed |