Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545552 | 0.98 | HRH3 (0.49) | HRH3ALDH1A1POLBMAPK1NPSR1 | |
| SCHEMBL16133545 | 0.92 | HRH3 (0.46) | HRH3ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL394558 | 0.83 | HRH3 (0.41) | HRH3ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8525180 | 0.82 | CYP2A6 (0.42) | HRH3ALDH1A1POLBMAPK1NPSR1 | |
| Hydrochloric Acid SCHEMBL2101720 | 0.82 | HRH3 (0.41) | HRH3ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL25358288 | 0.80 | HRH3 (0.48) | HRH3ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL13518434 | 0.80 | HRH3 (0.48) | HRH3ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL13227675 | 0.80 | HRH3 (0.48) | HRH3ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL3287322 | 0.80 | HRH3 (0.54) | HRH3ALDH1A1POLB | |
| SCHEMBL18494336 | 0.78 | CYP2A6 (0.42) | HRH3ALDH1A1POLBMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | disclosed |