Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11185382 | 0.92 | PRSS1 (0.62) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL4997061 | 0.92 | PRSS1 (0.62) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL3441517 | 0.90 | PRSS1 (0.50) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL44568 | 0.90 | PRSS1 (0.62) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL43233 | 0.90 | PRSS1 (0.67) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL25297232 | 0.88 | PRSS1 (0.70) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL20564639 | 0.88 | PRSS1 (0.70) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL21879662 | 0.88 | PRSS1 (0.70) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL43568 | 0.88 | PRSS1 (0.70) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL3680357 | 0.88 | PRSS1 (0.70) | PRSS1PRSS2PRSS3EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684254-A | Chemiluminescent probe for detecting ester hydrolase, preparation method and application thereof | 南京工业大学 | 2025-03-25 | — | — | CN | claimed |
| CN-119684254-A | Chemiluminescent probe for detecting ester hydrolase, preparation method and application thereof | 南京工业大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-112473593-A | Automatic production line of 2-4 bromomethyl phenyl propionic acid | 贵州天豪民族药业有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-112473593-A | Automatic production line of 2-4 bromomethyl phenyl propionic acid | 贵州天豪民族药业有限公司 | 2021-03-12 | — | — | CN | disclosed |
| US-4161531-A | Diuretic and saluretic 5-sulfamoylbenzoic acid derivatives carrying a heterocyclic substituent | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-17 | — | — | US | disclosed |
| US-4118397-A | DIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |
| US-4111953-A | DIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |
| US-4093735-A | DIURETICS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-06-06 | — | — | US | disclosed |
| US-4010273-A | DIURETICS, SALURETICS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |