Bromide

Bromide

SCHEMBL11545356

CCCCCCC(CC)[n+]1ccccc1C(C)C.[Br-]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 2/20 0.34
CHRM1 known ✓ P11229 2/20 0.34
ACHE known ✓ P22303 2/20 0.34
CHRM4 known ✓ P08173 1/20 0.34
CHRM5 known ✓ P08912 1/20 0.34
CHRM3 known ✓ P20309 1/20 0.34
OPRM1 known ✓ P35372 1/20 0.32
HTT P42858 2/20 0.35
HSP90AA1 P07900 2/20 0.34
RAD52 P43351 2/20 0.34
KMT2A Q03164 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
EGFR P00533 1/20 0.34
LMNA P02545 1/20 0.34
PLA2G1B P04054 1/20 0.34
ERBB2 P04626 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL8983476 0.71 RAD52 (0.47) HTTHSP90AA1RAD52KMT2ACHRM2
SCHEMBL5810925 0.70 SMN1; SMN2 (0.53) HTTHSP90AA1RAD52KMT2ACHRM2
SCHEMBL5301172 0.70 SMN1; SMN2 (0.53) HTTHSP90AA1RAD52KMT2ACHRM2
SCHEMBL5305269 0.70 SMN1; SMN2 (0.53) HTTHSP90AA1RAD52KMT2ACHRM2
SCHEMBL5286033 0.70 SMN1; SMN2 (0.53) HTTHSP90AA1RAD52KMT2ACHRM2
SCHEMBL5303543 0.70 SMN1; SMN2 (0.53) HTTHSP90AA1RAD52KMT2ACHRM2
SCHEMBL5818404 0.70 SMN1; SMN2 (0.53) HTTHSP90AA1RAD52KMT2ACHRM2
Hydrochloric Acid SCHEMBL11542156 0.70 SMN1; SMN2 (0.38) HTTHSP90AA1RAD52KMT2ACHRM2
Bromide SCHEMBL11544836 0.70 KCNH2 (0.38) HTTHSP90AA1RAD52KMT2ACHRM2
SCHEMBL29198529 0.69 SMN1; SMN2 (0.40) HTTHSP90AA1RAD52KMT2ACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4148738-A ALKYL OR AROMATIC SULFIDE OR POLYSULFIDE, QUATERNARY AMMONIUM HALIDE CHEVRON RESEARCH COMPANY (US) 1979-04-10 US disclosed