SCHEMBL11545600

SCHEMBL11545600

CCc1cc(C)nc2c(C)cccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.51
KDM4E B2RXH2 5/20 0.51
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
RAD52 P43351 3/20 0.46
HPGD P15428 2/20 0.46
POLB P06746 2/20 0.46
PSMD14 O00487 1/20 0.46
MITF O75030 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ELANE P08246 4/20 0.45
PARP1 P09874 1/20 0.45
CD38 P28907 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19178311 0.86 TP53 (0.51) TP53KDM4EKMT2AMEN1RAD52
SCHEMBL30587191 0.83 KDM4E (0.47) TP53KDM4EKMT2AMEN1LMNA
SCHEMBL11640173 0.83 KDM4E (0.65) KDM4EKMT2AMEN1RAD52HPGD
SCHEMBL2877622 0.83 KDM4E (0.47) TP53KDM4EKMT2AMEN1LMNA
SCHEMBL11570729 0.83 NR4A2 (0.61) KDM4EMAPTTDP1PARP1CD38
SCHEMBL27527696 0.81 KDM4E (0.46) TP53KDM4EKMT2AMEN1LMNA
SCHEMBL8072010 0.81 KDM4E (0.46) TP53KDM4EKMT2AMEN1LMNA
SCHEMBL8063650 0.81 KDM4E (0.39) TP53KDM4EKMT2AMEN1MAPT
SCHEMBL8024297 0.81 KDM4E (0.46) TP53KDM4EKMT2AMEN1LMNA
SCHEMBL12855181 0.80 KDM4E (0.54) KDM4EHPGDPOLBALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4167506-A Diazaphenalene derivatives and resin containing color compositions TEIJIN LIMITED (JP) 1979-09-11 US disclosed