Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547566 | 0.85 | ATM (0.51) | HTTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7247261 | 0.82 | HTT (0.54) | HTTSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL561284 | 0.80 | HTT (0.64) | HTTSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL12886144 | 0.78 | GAA (0.54) | HTTSMN1; SMN2GAAALDH1A1MEN1 | |
| Methyl 3,5-Dinitrobenzoate SCHEMBL418416 | 0.77 | SMN1; SMN2 (0.60) | HTTSMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL13879003 | 0.76 | HTT (0.58) | HTTSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL3853810 | 0.76 | KMT2A (0.56) | HTTSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL8762477 | 0.76 | HTT (0.59) | HTTSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL935580 | 0.75 | HTT (0.56) | HTTSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL38446 | 0.74 | HTT (0.58) | HTTSMN1; SMN2GAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138589-A | CHEMICAL INTERMEDIATES FOR COMPOUNDS USED AS X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4069250-A | X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1978-01-17 | — | — | US | disclosed |