Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550814 | 1.00 | MAPT (0.59) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL11549858 | 1.00 | MAPT (0.59) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL11548169 | 0.98 | MAPT (0.60) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL11545117 | 0.95 | MAPT (0.60) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL11420051 | 0.93 | MAPT (0.62) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL16516244 | 0.93 | MAPT (0.52) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL16516336 | 0.93 | MAPT (0.63) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL16742372 | 0.93 | MAPT (0.63) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL18109929 | 0.93 | MAPT (0.52) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL17916659 | 0.93 | MAPT (0.52) | MAPTALDH1A1LMNATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |