Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2099319 | 0.88 | TSHR (0.77) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL5887492 | 0.87 | TSHR (0.81) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| Ethylene Glycol SCHEMBL19639819 | 0.87 | TSHR (0.91) | TSHRALDH1A1CYP3A4MAPK1HPGD | |
| Ethylene Glycol SCHEMBL20838524 | 0.87 | TSHR (0.91) | TSHRALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL74390 | 0.87 | TSHR (0.73) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL869655 | 0.85 | TSHR (0.67) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL16765797 | 0.84 | TSHR (1.00) | TSHRALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL29596375 | 0.84 | TSHR (1.00) | TSHRALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL20609794 | 0.84 | TSHR (1.00) | TSHRALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL14869 | 0.84 | TSHR (1.00) | TSHRALDH1A1CYP3A4MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037819-A1 | OPTICAL ISOMER | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2018-02-08 | — | — | US | disclosed |
| US-4143020-A | COPOLYMERS OF SULFONIC ACID MONOMERS | ROHM AND HAAS COMPANY (US) | 1979-03-06 | — | — | US | disclosed |
| US-4131736-A | Polymers of sulfonic acid monomers | ROHM AND HAAS COMPANY (US) | 1978-12-26 | — | — | US | disclosed |