Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.62 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9072471 | 0.81 | GCK (0.56) | GCKKDRALDH1A1MAPTGAA | |
| SCHEMBL11970994 | 0.81 | KDR (0.57) | GCKKDRDHODHMEN1KMT2A | |
| SCHEMBL10157664 | 0.81 | GCK (0.52) | GCKKDRKMT2AALDH1A1MAPT | |
| SCHEMBL13531372 | 0.77 | GCK (0.53) | GCKDHODHMEN1KMT2AALDH1A1 | |
| SCHEMBL1330737 | 0.77 | GCK (1.00) | GCKMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL23631384 | 0.77 | PPIA (0.66) | GCKGRM5 | |
| Hydrochloric Acid SCHEMBL1330945 | 0.76 | GCK (0.97) | GCKKMT2AALDH1A1MAPTGAA | |
| SCHEMBL8657033 | 0.74 | PPIA (0.50) | GCKKDRMEN1KMT2AALDH1A1 | |
| SCHEMBL29286150 | 0.73 | GCK (0.46) | GCKKDRMEN1KMT2AALDH1A1 | |
| SCHEMBL30968561 | 0.73 | GCK (0.46) | GCKKDRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179563-A | COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY (US) | 1979-12-18 | — | — | US | claimed |
| US-4179563-A | COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY (US) | 1979-12-18 | — | — | US | disclosed |