SCHEMBL11547736

SCHEMBL11547736

Fc1ccccc1Oc1cccnc1C1CNCCN1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 15/20 0.48
HTR1A P08908 14/20 0.48
SLC6A4 P31645 6/20 0.48
SLC6A3 Q01959 7/20 0.45
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11544006 0.99 SLC6A2 (0.47) SLC6A2HTR1ASLC6A4SLC6A3KDM4E
SCHEMBL11544724 0.84 SLC6A4 (0.42) SLC6A2HTR1ASLC6A4SLC6A3
SCHEMBL6131954 0.83 CXCR4 (0.36) SLC6A2HTR1ASLC6A4SLC6A3
Hydrochloric Acid SCHEMBL11543158 0.83 SLC6A4 (0.41) SLC6A2HTR1ASLC6A4SLC6A3
SCHEMBL11545035 0.79 HTR2C (0.41) SLC6A2HTR1ASLC6A4SLC6A3
SCHEMBL11545714 0.76 HTR2C (0.46) SLC6A2HTR1ASLC6A4SLC6A3
SCHEMBL7535268 0.75 PARP1 (0.36)
SCHEMBL11544045 0.72 CXCR4 (0.34)
SCHEMBL2771921 0.72 SLC6A2 (0.36) SLC6A2HTR1ASLC6A4SLC6A3
SCHEMBL8415186 0.72 CXCR4 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4179563-A COGNITION ACTIVATORS WARNER-LAMBERT COMPANY (US) 1979-12-18 US disclosed