Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547097 | 0.89 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11548540 | 0.87 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11544085 | 0.87 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10879037 | 0.86 | MAPT (0.78) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3922061 | 0.83 | MAPT (0.54) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3922397 | 0.82 | MAPT (0.52) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5203582 | 0.82 | MAPT (0.52) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL15156144 | 0.82 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL31118853 | 0.79 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL189811 | 0.79 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |