Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TNF | P01375 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11732858 | 0.85 | SRC (0.48) | ALDH1A1SRCKDM4EHSD17B10SMN1; SMN2 | |
| Pirolate SCHEMBL11546568 | 0.84 | SRC (0.51) | ALDH1A1HPGDSRCKDM4EHSD17B10 | |
| SCHEMBL11734775 | 0.82 | SRC (0.53) | ALDH1A1GLAHPGDSRCKDM4E | |
| SCHEMBL11552437 | 0.82 | SRC (0.53) | ALDH1A1GLAHPGDSRCKDM4E | |
| SCHEMBL11550171 | 0.81 | SRC (0.50) | ALDH1A1HPGDSRCKDM4EHSD17B10 | |
| SCHEMBL11549583 | 0.80 | SRC (0.56) | ALDH1A1GLAHPGDSRCKDM4E | |
| SCHEMBL11551636 | 0.78 | SRC (0.56) | ALDH1A1GLAHPGDSRCKDM4E | |
| SCHEMBL11549725 | 0.78 | SRC (0.43) | ALDH1A1HPGDSRCKDM4EHSD17B10 | |
| SCHEMBL11548055 | 0.77 | SRC (0.43) | ALDH1A1HPGDSRCKDM4EHSD17B10 | |
| SCHEMBL11548520 | 0.77 | SRC (0.43) | ALDH1A1HPGDSRCKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134981-A | ANTIALLERGENS | PFIZER INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4120962-A | Fused pyrimidin-4(3H)-ones as antiallergy agents | PFIZER INC. (US) | 1978-10-17 | — | — | US | disclosed |
| US-4044134-A | FUSED WITH QUINOLINE OR PYRIDINE, 2-METHYL, ETHYL, OR ACETYL GROUP | PFIZER INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-3974161-A | Fused pyrimidin-4(3H)-ones as antiallergy agents | PFIZER INC. (US) | 1976-08-10 | — | — | US | disclosed |