Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | MGLL | Q99685 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 3/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CHAT | P28329 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548251 | 1.00 | CA1 (0.60) | CA1MGLLMAOBNFE2L2CYP19A1 | |
| SCHEMBL4004894 | 1.00 | CA1 (0.60) | CA1MGLLMAOBNFE2L2CYP19A1 | |
| SCHEMBL4004892 | 1.00 | CA1 (0.60) | CA1MGLLMAOBNFE2L2CYP19A1 | |
| SCHEMBL83379 | 0.97 | MAOB (0.62) | CA1MGLLMAOBNFE2L2CYP19A1 | |
| SCHEMBL76158 | 0.97 | CA1 (0.62) | CA1MGLLMAOBNFE2L2CYP19A1 | |
| SCHEMBL11548871 | 0.97 | MAOB (0.62) | CA1MGLLMAOBNFE2L2CYP19A1 | |
| SCHEMBL83380 | 0.97 | MAOB (0.62) | CA1MGLLMAOBNFE2L2CYP19A1 | |
| SCHEMBL11548873 | 0.97 | MAOB (0.62) | CA1MGLLMAOBNFE2L2CYP19A1 | |
| SCHEMBL76159 | 0.97 | CA1 (0.62) | CA1MGLLMAOBNFE2L2CYP19A1 | |
| SCHEMBL9171323 | 0.97 | CA1 (0.62) | CA1MGLLMAOBNFE2L2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4158099-A | FROM SCHIFF BASES AND BIPHENYL COMPOUND | CIBA-GEIGY AG (CH) | 1979-06-12 | — | — | US | disclosed |
| US-3991049-A | Aromatic compounds containing ethylene double bonds, processes for their manufacture and use | CIBA-GEIGY AG (CH) | 1976-11-09 | — | — | US | disclosed |