Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | RARA | P10276 | 1/20 | 0.66 |
| ▸ | MTOR | P42345 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 8/20 | 0.59 |
| ▸ | THRA | P10827 | 6/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11551572 | 1.00 | RARB (0.66) | RARBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11552789 | 1.00 | RARB (0.66) | RARBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11550621 | 1.00 | RARB (0.66) | RARBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9856064 | 1.00 | RARB (0.66) | RARBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11545763 | 1.00 | RARB (0.66) | RARBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11551026 | 1.00 | RARB (0.66) | RARBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11554229 | 1.00 | RARB (0.66) | RARBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11547651 | 1.00 | RARB (0.66) | RARBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11547546 | 1.00 | RARB (0.66) | RARBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9799875 | 1.00 | RARB (0.66) | RARBMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136053-A | BIPHENYL ESTERS AND LIQUID CRYSTALLINE MIXTURES COMPRISING THEM | MERCK PATENT GESELLSCHAFT MIT BESCHANKTER HAFTUNG (DE) | 1979-01-23 | — | — | US | disclosed |
| US-4065489-A | Biphenyl esters and liquid crystalline mixtures comprising them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-12-27 | — | — | US | disclosed |