Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546938 | 0.82 | SRC (0.62) | SRCKDM4EGAAPDE3BPDE3A | |
| SCHEMBL27167377 | 0.81 | KDM4E (0.72) | KDM4EGAAPDE3BPDE3AMAPK1 | |
| Pirolate SCHEMBL11546568 | 0.78 | SRC (0.51) | SRCKDM4EGAAPDE3BPDE3A | |
| SCHEMBL11549583 | 0.77 | SRC (0.56) | SRCKDM4EGAAPDE3BPDE3A | |
| SCHEMBL11551636 | 0.77 | SRC (0.56) | SRCKDM4EGAAPDE3BPDE3A | |
| SCHEMBL11553496 | 0.76 | SRC (0.55) | SRCKDM4EGAAPDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL11732858 | 0.75 | SRC (0.48) | SRCKDM4EGAAPDE3BPDE3A | |
| SCHEMBL11734775 | 0.74 | SRC (0.53) | SRCKDM4EGAAPDE3BPDE3A | |
| SCHEMBL11552437 | 0.74 | SRC (0.53) | SRCKDM4EGAAPDE3BPDE3A | |
| SCHEMBL11550171 | 0.74 | SRC (0.50) | SRCKDM4EGAAPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134981-A | ANTIALLERGENS | PFIZER INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4120962-A | Fused pyrimidin-4(3H)-ones as antiallergy agents | PFIZER INC. (US) | 1978-10-17 | — | — | US | disclosed |
| US-3974161-A | Fused pyrimidin-4(3H)-ones as antiallergy agents | PFIZER INC. (US) | 1976-08-10 | — | — | US | disclosed |