Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | PGR | P06401 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.54 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11604888 | 0.94 | TDP1 (0.78) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL11611462 | 0.94 | TDP1 (0.78) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL11551944 | 0.91 | TDP1 (0.73) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL11668130 | 0.90 | TDP1 (0.73) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL11179454 | 0.89 | TDP1 (0.70) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL11615495 | 0.89 | TDP1 (0.74) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL11181429 | 0.88 | TDP1 (0.73) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL11419679 | 0.88 | TDP1 (0.72) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| Cefuracetime SCHEMBL615048 | 0.88 | TDP1 (0.87) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| Cefuracetime SCHEMBL11611927 | 0.88 | TDP1 (0.87) | TDP1NR1I2HSD17B10PGRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165430-A | HIGH ACTIVITY AGAINST GRAMNEGATIVE BACTERIA | GLAXO LABORATORIES LIMITED (GB) | 1979-08-21 | — | — | US | disclosed |
| US-4144393-A | 3-Acetoxymethyl cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyiminoarylacetamido group | GLAXO LABORATORIES LIMITED (GB) | 1979-03-13 | — | — | US | disclosed |