Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258476 | 0.82 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL11547501 | 0.81 | CYP1A2 (0.51) | SLC6A4SLC6A2SLC6A3CYP2D6CXCR3 | |
| Iodide SCHEMBL11547732 | 0.80 | CYP1A2 (0.50) | SLC6A4SLC6A2SLC6A3CYP2D6CXCR3 | |
| SCHEMBL11539003 | 0.78 | SLC6A2 (0.59) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL11539000 | 0.78 | SLC6A2 (0.59) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL11541919 | 0.77 | SLC6A2 (0.58) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL11541922 | 0.77 | SLC6A2 (0.58) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL11257297 | 0.77 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL11551974 | 0.76 | GRIN2B (0.45) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL11551737 | 0.76 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141893-A | Decahydrocyclopent[c]azepines | ELI LILLY AND COMPANY (US) | 1979-02-27 | — | — | US | disclosed |