Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11861040 | 0.84 | CYP3A4 (0.48) | CYP3A4MMP9MMP8MMP14ALDH1A1 | |
| SCHEMBL5469162 | 0.82 | CYP3A4 (0.78) | CYP3A4MMP9MMP8MMP14ALDH1A1 | |
| SCHEMBL2241603 | 0.82 | CYP3A4 (0.78) | CYP3A4MMP9MMP8MMP14ALDH1A1 | |
| SCHEMBL4285682 | 0.81 | CYP3A4 (0.57) | CYP3A4MMP9MMP8MMP14ALDH1A1 | |
| SCHEMBL5481187 | 0.80 | CYP3A4 (0.75) | CYP3A4MMP9MMP8MMP14ALDH1A1 | |
| SCHEMBL8518572 | 0.80 | CYP3A4 (0.75) | CYP3A4MMP9MMP8MMP14ALDH1A1 | |
| SCHEMBL5469337 | 0.80 | CYP3A4 (0.75) | CYP3A4MMP9MMP8MMP14ALDH1A1 | |
| SCHEMBL5474996 | 0.80 | CYP3A4 (0.75) | CYP3A4MMP9MMP8MMP14ALDH1A1 | |
| SCHEMBL1835296 | 0.80 | CYP3A4 (0.74) | CYP3A4MMP9MMP8MMP14ALDH1A1 | |
| SCHEMBL11808812 | 0.79 | CYP3A4 (0.44) | CYP3A4MMP9MMP8MMP14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141851-A | HYDROCARBYLOXYALKYLENESILANES, HYDRAULIC FLUIDS | CASTROL LIMITED (GB) | 1979-02-27 | — | — | US | claimed |