Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 18/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.69 |
| ▸ | CNR1 | P21554 | 2/20 | 0.62 |
| ▸ | CNR2 | P34972 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | PLD2 | O14939 | 1/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | C5 | P01031 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | FYN | P06241 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30558217 | 0.94 | ESR1 (0.70) | ESR1ESR2CNR1MEN1PLD2 | |
| SCHEMBL11546753 | 0.93 | ESR1 (0.69) | ESR1ESR2CNR1CNR2MEN1 | |
| SCHEMBL6425122 | 0.92 | ESR1 (0.68) | ESR1ESR2CNR1CNR2TDP1 | |
| SCHEMBL7075381 | 0.92 | ESR1 (0.72) | ESR1ESR2CNR1CNR2MEN1 | |
| SCHEMBL7075631 | 0.91 | ESR1 (0.74) | ESR1ESR2CNR1CNR2MEN1 | |
| SCHEMBL7075664 | 0.91 | ESR1 (0.74) | ESR1ESR2CNR1CNR2MEN1 | |
| SCHEMBL11546633 | 0.90 | ESR1 (0.67) | ESR1ESR2CNR1MEN1PLD2 | |
| SCHEMBL11550082 | 0.90 | ESR1 (0.63) | ESR1ESR2CNR1MEN1PLD2 | |
| SCHEMBL7971665 | 0.88 | ESR1 (0.66) | ESR1ESR2CNR1MEN1PLD2 | |
| SCHEMBL11551310 | 0.86 | ESR1 (0.65) | ESR1ESR2CNR1CNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |