Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | PDE1A | P54750 | 1/20 | 0.49 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24066443 | 0.89 | PDE10A (0.60) | PDE10AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL10205836 | 0.87 | PDE10A (0.58) | PDE10AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL26569656 | 0.82 | PDE10A (0.53) | PDE10AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL16169860 | 0.81 | PDE10A (0.56) | PDE10AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL2125225 | 0.81 | PDE10A (1.00) | PDE10AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL30999690 | 0.79 | PDE10A (0.96) | PDE10AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL27610987 | 0.79 | PDE10A (0.96) | PDE10AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL6858227 | 0.79 | PDE10A (0.96) | PDE10AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL24268258 | 0.79 | PDE10A (0.55) | PDE10AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL65673 | 0.78 | KMT2A (0.59) | KDM4EALDH1A1MAPTMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171444-A | REACTING A (HETERO-)AROMATIC KETONE, AMMONIA, AND AN ALIPHATIC ALDEHYDE, DEHYDRATING-DEHYDROGENATION CATALYSTS | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-10-16 | — | — | US | disclosed |