Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 9/20 | 0.78 |
| ▸ | MAOA | P21397 | 6/20 | 0.58 |
| ▸ | MAOB | P27338 | 6/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551706 | 0.95 | NISCH (0.81) | NISCHMAOAMAOBTAAR1TSHR | |
| Hydrochloric Acid SCHEMBL11550188 | 0.93 | NISCH (0.78) | NISCHMAOAMAOBTAAR1TSHR | |
| SCHEMBL7547171 | 0.88 | NISCH (1.00) | NISCHMAOAMAOBTAAR1TSHR | |
| SCHEMBL7553404 | 0.82 | NISCH (0.87) | NISCHMAOAMAOBTAAR1TSHR | |
| SCHEMBL11603227 | 0.81 | NISCH (0.59) | NISCHMAOAMAOBTAAR1TSHR | |
| SCHEMBL7548077 | 0.80 | NISCH (0.82) | NISCHMAOAMAOBTAAR1TSHR | |
| SCHEMBL7548070 | 0.80 | NISCH (0.82) | NISCHMAOAMAOBTAAR1TSHR | |
| SCHEMBL7550483 | 0.76 | NISCH (0.75) | NISCHMAOAMAOBTAAR1TSHR | |
| Midaglizole SCHEMBL30029057 | 0.75 | NISCH (0.74) | NISCHMAOAMAOBTAAR1TSHR | |
| Midaglizole SCHEMBL114554 | 0.75 | NISCH (0.74) | NISCHMAOAMAOBTAAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136188-A | TREATMENT OF DIABETES WITH 2-SUBSTITUTED-1,3-DIAZACYCLIC COMPOUNDS | DAIICHI SEIYAKU CO., LTD. (JP) | 1979-01-23 | — | — | US | disclosed |