Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6260384 | 0.93 | CA1 (0.50) | — | |
| Hydrochloric Acid SCHEMBL28137502 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL28399644 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL60758 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL11843791 | 0.93 | — | — | |
| Bromide SCHEMBL28002893 | 0.93 | — | — | |
| Bromide SCHEMBL9945 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL18222489 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL18222488 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL27814829 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4149000-A | ANTAGONISTS OF NARCOTIC ANALGESICS | STERLING DRUG INC. (US) | 1979-04-10 | — | — | US | disclosed |
| US-4009171-A | ANTAGONISTS OF NARCOTIC ANALGESICS | STERLING DRUG INC. (US) | 1977-02-22 | — | — | US | disclosed |