Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114681 | 0.85 | PIK3CA (0.81) | PIK3CAMTOR | |
| SCHEMBL115503 | 0.85 | PIK3CA (0.81) | PIK3CAMTOR | |
| SCHEMBL114758 | 0.85 | PIK3CA (0.81) | PIK3CAMTOR | |
| SCHEMBL113915 | 0.85 | PIK3CA (0.82) | PIK3CAMTOR | |
| SCHEMBL114182 | 0.85 | PIK3CA (0.82) | PIK3CAMTOR | |
| SCHEMBL113913 | 0.85 | PIK3CA (0.82) | PIK3CAMTOR | |
| SCHEMBL115003 | 0.83 | PIK3CA (0.82) | PIK3CAMTOR | |
| SCHEMBL7770494 | 0.82 | PIK3CA (0.80) | PIK3CAMTOR | |
| SCHEMBL115496 | 0.79 | PIK3CA (0.81) | PIK3CAMTOR | |
| SCHEMBL115526 | 0.79 | PIK3CA (0.77) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424859-A1 | INHIBITORS OF PI3 KINASE AND / OR MTOR | Amgen, Inc (US) | 2012-03-07 | — | — | EP | claimed |
| WO-2010126895-A1 | INHIBITORS OF PI3 KINASE AND / OR MTOR | AMGEN INC. (US) | 2010-11-04 | — | — | WO | claimed |