Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | LYN | P07948 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557174 | 1.00 | PI4KB (0.51) | PI4KBGFERALDH1A1HPGDKMT2A | |
| SCHEMBL11152584 | 0.85 | PI4KB (0.34) | PI4KBKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL11159784 | 0.85 | ABL1 (0.42) | PI4KBALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL11555815 | 0.85 | PI4KB (0.41) | PI4KBALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11555819 | 0.85 | PI4KB (0.41) | PI4KBALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11260958 | 0.83 | PI4KB (0.35) | PI4KBKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL11263874 | 0.83 | PI4KB (0.35) | PI4KBKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL11263866 | 0.83 | PI4KB (0.35) | PI4KBKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL11147950 | 0.82 | PI4KB (0.33) | PI4KBKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL11147951 | 0.82 | PI4KB (0.33) | PI4KBKMT2ASMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150028-A | Antiviral thiazolinyl benzimidazoles | ELI LILLY AND COMPANY (US) | 1979-04-17 | — | — | US | claimed |