Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MGLL | Q99685 | 4/20 | 0.61 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565392 | 1.00 | POLB (0.62) | POLBMGLLSCN5AABCB11CYP3A4 | |
| SCHEMBL11075289 | 1.00 | POLB (0.62) | POLBMGLLSCN5AABCB11CYP3A4 | |
| SCHEMBL2310585 | 1.00 | POLB (0.62) | POLBMGLLSCN5AABCB11CYP3A4 | |
| SCHEMBL11560046 | 1.00 | POLB (0.62) | POLBMGLLSCN5AABCB11CYP3A4 | |
| SCHEMBL11564179 | 1.00 | POLB (0.62) | POLBMGLLSCN5AABCB11CYP3A4 | |
| SCHEMBL29114255 | 1.00 | POLB (0.62) | POLBMGLLSCN5AABCB11CYP3A4 | |
| SCHEMBL3944091 | 0.98 | POLB (0.64) | POLBMGLLSCN5AABCB11CYP3A4 | |
| SCHEMBL14149520 | 0.93 | SCN5A (0.68) | POLBMGLLSCN5AABCB11CYP3A4 | |
| SCHEMBL11496353 | 0.89 | POLB (0.54) | POLBMGLLSCN5AABCB11CYP3A4 | |
| SCHEMBL11496351 | 0.89 | POLB (0.54) | POLBMGLLSCN5AABCB11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154756-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |