Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 16/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 13/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.34 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1050809 | 0.98 | LPAR3 (0.50) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| Ammonia Solution, Strong SCHEMBL25395021 | 0.96 | LPAR3 (0.48) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL15153098 | 0.96 | LPAR3 (0.48) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL28396482 | 0.96 | LPAR3 (0.48) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL11752955 | 0.92 | LPAR3 (0.48) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL28480889 | 0.90 | LPAR3 (0.62) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL1049519 | 0.90 | LPAR3 (0.57) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL5453966 | 0.89 | LPAR3 (0.60) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL1051569 | 0.89 | LPAR3 (0.60) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL4436299 | 0.89 | LPAR3 (0.60) | LPAR3LPAR2LPAR1LPAR6LPAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137189-A | POLYSILOXANE, CHLORENDATES AND METAL PHOSPHORODITHIOATES OR DITHIOCARBAMATES | DOW CORNING CORPORATION (US) | 1979-01-30 | — | — | US | disclosed |