⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11584346 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL27739788 | 0.96 | — | — | |
| SCHEMBL3430780 | 0.83 | — | — | |
| SCHEMBL27904616 | 0.81 | — | — | |
| SCHEMBL17804066 | 0.78 | — | — | |
| SCHEMBL8250722 | 0.78 | — | — | |
| SCHEMBL18677542 | 0.73 | — | — | |
| SCHEMBL8610688 | 0.70 | — | — | |
| SCHEMBL115628 | 0.67 | — | — | |
| SCHEMBL11274704 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2202 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108623496-B | Preparation method of 3-ethyl-4-fluorobenzonitrile | 上海特化医药科技有限公司 | 2022-11-08 | — | — | CN | claimed |
| US-20210363149-A1 | PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF | ABBVIE INC (US) | 2021-11-25 | — | — | US | claimed |
| CN-212776234-U | Buffer tank for producing ethyl boric acid | 苏州友硼光电材料有限公司 | 2021-03-23 | — | — | CN | claimed |
| EP-3362455-A1 | PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF | AbbVie Inc. (US) | 2018-08-22 | — | — | EP | claimed |
| US-20170129902-A1 | PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-alpha]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-05-11 | — | — | US | claimed |
| WO-2017066775-A1 | PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF | ABBVIE INC. (US) | 2017-04-20 | — | — | WO | claimed |
| US-9416084-B2 | Method of producing ingenol-3-angelate | LEO LABORATORIES LIMITED (IE) | 2016-08-16 | — | — | US | claimed |
| US-8846915-B2 | Process for the manufacture of rosuvastatin calcium using crystalline rosuvastatin ethyl ester | AUROBINDO PHARMA LTD. (IN) | 2014-09-30 | — | — | US | claimed |
| EP-2467363-A1 | PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM USING CRYSTALLINE ROSUVASTATIN ETHYL ESTER | Aurobindo Pharma Limited (IN) | 2012-06-27 | — | — | EP | claimed |
| US-20120149905-A1 | PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM USING CRYSTALLINE ROSUVASTATIN ETHYL ESTER | AUROBINDO PHARMA LTD (IN) | 2012-06-14 | — | — | US | claimed |
| WO-2011021058-A1 | PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM USING CRYSTALLINE ROSUVASTATIN ETHYL ESTER | AUROBINDO PHARMA LIMITED (IN) | 2011-02-24 | — | — | WO | claimed |
| WO-2009118598-A1 | PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM WITH HIGH PURITY | AUROBINDO PHARMA LIMITED (IN) | 2009-10-01 | — | — | WO | claimed |
| US-7091290-B2 | Method for preparing homo-and co-polymers of cyclic olefin compounds using an organic boron compound as a catalyst activator | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2006-08-15 | — | — | US | claimed |
| US-20050245703-A1 | addition polymerization of nonaromatic cyclic olefins, such as alkylnorbornenes and dicyclopentadienes, in the presence of a catalyst complex also including a nickel II carboxylate and an aluminoxane compound; high molecular weight polymer in high yields; gelation inhibition | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2005-11-03 | — | — | US | claimed |
| US-4339351-A | REACTION PRODUCT OF GRIGNARD REAGENT AND BORON COMPOUND AS CATALYST SUPPORT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-07-13 | — | — | US | claimed |
| US-12637672-B2 | Oligonucleotide compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2026-05-26 | — | — | US | disclosed |
| WO-2026107431-A1 | STEREOSELECTIVE SYNTHESIS OF L,2-CIS-2-AMINOGLYCOSIDES | BRANDEIS UNIVERSITY (US) | 2026-05-21 | — | — | WO | disclosed |
| EP-0189181-A2 | Method of producing silicon carbide base sintered material containing boron as sintering assistant | NISSAN MOTOR CO., LTD. (JP) | 1986-07-30 | — | — | EP | disclosed |
| US-4401797-A | ADDUCT OF DIHYDROXYPROPYL (METH)ACRYLATE AND BORONIC ACID | SYNTEX (U.S.A.) INC. (US) | 1983-08-30 | — | — | US | disclosed |
| US-4381345-A | Pretreatment of glucose feedstock with reducing agents | UOP INC. (US) | 1983-04-26 | — | — | US | disclosed |