SCHEMBL11563232

SCHEMBL11563232

C[PH](c1ccccc1)(c1ccccc1)c1ccccc1.ClSc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MGLL Q99685 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL397524 0.80
SCHEMBL8952 0.80 TSHR (0.39) ALDH1A1
SCHEMBL29105910 0.78 TSHR (0.33) ALDH1A1
SCHEMBL17431672 0.77 TSHR (0.37) ALDH1A1
SCHEMBL2789002 0.77 TSHR (0.37) ALDH1A1
Fluoride SCHEMBL943902 0.77 HPGD (0.50) MAPTHPGDSMN1; SMN2MGLLHSD17B10
Iodide SCHEMBL2117427 0.77 TSHR (0.37) ALDH1A1
Phosphine SCHEMBL5003432 0.77 TSHR (0.37) ALDH1A1
SCHEMBL8967804 0.77 TSHR (0.37) ALDH1A1
Hydrochloric Acid SCHEMBL11583626 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003420-A1 Arylthiovinylcyclopropanecarboxylate insecticide and intermediates therefor FMC Corporation (US) 1979-08-08 EP disclosed