Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558806 | 0.96 | DPP4 (0.35) | TSHRDPP4CA12CA1CA9 | |
| SCHEMBL11558627 | 0.95 | DPP4 (0.35) | TSHRDPP4CA12CA1CA9 | |
| SCHEMBL11562630 | 0.95 | TSHR (0.39) | TSHRDPP4CA12CA1CA9 | |
| SCHEMBL11561648 | 0.94 | TSHR (0.41) | TSHRDPP4CA12CA1CA9 | |
| SCHEMBL11567141 | 0.92 | DPP4 (0.37) | TSHRDPP4CA12CA1CA9 | |
| SCHEMBL11563035 | 0.90 | TSHR (0.38) | TSHRDPP4KDM4EALDH1A1LMNA | |
| SCHEMBL11561239 | 0.89 | DPP4 (0.40) | TSHRDPP4KDM4EALDH1A1LMNA | |
| SCHEMBL11567841 | 0.89 | DPP4 (0.34) | TSHRDPP4KDM4EALDH1A1HPGD | |
| SCHEMBL11563939 | 0.89 | TSHR (0.38) | TSHRDPP4CA12CA1CA9 | |
| SCHEMBL11561804 | 0.89 | TSHR (0.38) | TSHRDPP4CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148626-A | Herbicidal agents | THE BOOTS COMPANY LIMITED (GB) | 1979-04-10 | — | — | US | disclosed |