Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CASR | P41180 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31195239 | 0.87 | CA1 (0.71) | ALDH1A1CA1CA2KMT2AMEN1 | |
| SCHEMBL11794595 | 0.85 | CA1 (0.54) | ALDH1A1LMNAMITFHTTNOD2 | |
| SCHEMBL28816108 | 0.83 | CA1 (0.56) | ALDH1A1LMNAMITFHTTNOD2 | |
| SCHEMBL13724576 | 0.82 | CASR (0.54) | ALDH1A1LMNAMITFHTTNOD2 | |
| SCHEMBL9373685 | 0.81 | KMT2A (0.62) | ALDH1A1LMNAHTTKMT2AMEN1 | |
| SCHEMBL11881914 | 0.80 | FNTA (0.58) | ALDH1A1LMNACA1CA2MAPK1 | |
| SCHEMBL11516870 | 0.80 | CA1 (0.54) | ALDH1A1LMNAMITFHTTNOD2 | |
| Potassium SCHEMBL11516876 | 0.80 | CA1 (0.54) | ALDH1A1LMNAMITFHTTNOD2 | |
| SCHEMBL5705537 | 0.80 | CA1 (0.57) | ALDH1A1LMNAMITFHTTNOD2 | |
| SCHEMBL13723881 | 0.79 | MAPT (0.62) | ALDH1A1LMNAMITFHTTNOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141734-A | SUBSTITUTED ORGANIC DI- OR TRISULFIDE ANTIDEPOSIT AGENTS | CIBA-GEIBY AG (CH) | 1979-02-27 | — | — | US | disclosed |