Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526730 | 0.95 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11524967 | 0.89 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11524956 | 0.86 | MAPT (0.47) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11525672 | 0.85 | NPC1 (0.49) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11520957 | 0.84 | MAPT (0.53) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11524962 | 0.83 | MAPT (0.47) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11564518 | 0.83 | CHRNB4 (0.47) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11525675 | 0.82 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11524981 | 0.81 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11524969 | 0.81 | CHRNB4 (0.54) | MAPTNPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174321-A | POLYMERIC MOLDING MATERIALS | EASTMAN KODAK COMPANY (US) | 1979-11-13 | — | — | US | disclosed |