Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555374 | 0.89 | MAOB (0.57) | HPGDMEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL3811329 | 0.88 | MAOB (0.71) | HPGDMEN1ALDH1A1KMT2AMAOB | |
| SCHEMBL29586539 | 0.85 | NPC1 (0.74) | HPGDMEN1ALDH1A1KMT2AMAOB | |
| SCHEMBL3811897 | 0.85 | NPC1 (0.74) | HPGDMEN1ALDH1A1KMT2AMAOB | |
| SCHEMBL11568624 | 0.85 | MAOB (0.56) | HPGDMEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL8983990 | 0.84 | MAOB (0.55) | HPGDMEN1ALDH1A1KMT2AMAOB | |
| SCHEMBL11559411 | 0.84 | MAOB (0.55) | HPGDMEN1ALDH1A1KMT2AMAOB | |
| SCHEMBL3813064 | 0.84 | NPC1 (0.71) | HPGDMEN1ALDH1A1KMT2APOLB | |
| SCHEMBL29586008 | 0.83 | NPC1 (0.58) | HPGDMEN1ALDH1A1KMT2APOLB | |
| SCHEMBL8983936 | 0.83 | NPC1 (0.58) | HPGDMEN1ALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163746-A | ANABOLIC, 5-METHYL-7-ALKOXYISOFLAVONES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1979-08-07 | — | — | US | disclosed |