Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.71 |
| ▸ | HRH1 | P35367 | 4/20 | 0.71 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3427848 | 0.88 | HTR2A (0.69) | HTR2AHRH1AOC3RIPK1LMNA | |
| SCHEMBL19121804 | 0.88 | HTR2A (0.69) | HTR2AHRH1AOC3RIPK1LMNA | |
| SCHEMBL22515947 | 0.88 | HTR2A (0.69) | HTR2AHRH1AOC3RIPK1LMNA | |
| SCHEMBL11387932 | 0.85 | HTR2A (0.53) | HTR2AHRH1AOC3RIPK1SLC6A4 | |
| SCHEMBL28588039 | 0.82 | HTR2A (0.48) | HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL11374749 | 0.82 | HTR2A (0.96) | HTR2AHRH1LMNACYP1A2CHRM2 | |
| SCHEMBL11566392 | 0.81 | UTS2R (0.49) | HTR2AHRH1CHRM2CHRM4CHRM5 | |
| SCHEMBL5542831 | 0.80 | HTR2A (0.47) | HTR2AHRH1AOC3RIPK1TAAR1 | |
| SCHEMBL5542840 | 0.80 | HTR2A (0.47) | HTR2AHRH1AOC3RIPK1LMNA | |
| SCHEMBL11390895 | 0.80 | HTR2A (0.47) | HTR2AHRH1AOC3SLC6A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002604-A1 | Quaternary ammonium salts, and their formulations and preparation | ELI LILLY AND COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |