Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1180196 | 0.83 | GAA (0.41) | KDM4ETDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL30823619 | 0.83 | GAA (0.41) | KDM4ETDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL6602936 | 0.81 | CYP3A4 (0.46) | NQO2MTNR1AIDH1CYP3A4CYP2C19 | |
| SCHEMBL21066919 | 0.81 | PTGER1 (0.44) | TDP1L3MBTL1MEN1KMT2AMPL | |
| SCHEMBL5189165 | 0.80 | TDP1 (0.45) | CYP3A4KDM4ETDP1L3MBTL1MEN1 | |
| SCHEMBL9316805 | 0.78 | NPC1 (0.47) | MTNR1AIDH1KDM4EL3MBTL1MEN1 | |
| SCHEMBL5763555 | 0.77 | TP53 (0.46) | MTNR1ACA2 | |
| SCHEMBL816601 | 0.77 | GAA (0.39) | CYP3A4CYP2C19CYP2C9KDM4ETDP1 | |
| SCHEMBL5718625 | 0.77 | GAA (0.39) | CYP3A4CYP2C19CYP2C9KDM4ETDP1 | |
| SCHEMBL30723203 | 0.77 | GAA (0.39) | CYP3A4CYP2C19CYP2C9KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | disclosed |