Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.50 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.42 |
| ▸ | LRAT | O95237 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21105031 | 1.00 | GBA1 (0.50) | GBA1FUCA1SILRATMGAM | |
| SCHEMBL11049253 | 0.85 | — | — | |
| SCHEMBL5805992 | 0.85 | — | — | |
| SCHEMBL133955 | 0.81 | FUCA1 (0.63) | GBA1FUCA1SILRATMGAM | |
| SCHEMBL18460913 | 0.81 | FUCA1 (0.63) | GBA1FUCA1SILRATMGAM | |
| SCHEMBL21105130 | 0.81 | FUCA1 (0.63) | GBA1FUCA1SILRATMGAM | |
| SCHEMBL11044942 | 0.81 | FUCA1 (0.63) | GBA1FUCA1SILRATMGAM | |
| Bromide SCHEMBL6284958 | 0.79 | FUCA1 (0.60) | GBA1FUCA1SILRATMGAM | |
| SCHEMBL19442151 | 0.76 | — | — | |
| SCHEMBL20220890 | 0.73 | FUCA1 (0.42) | GBA1FUCA1SIMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4049498-A | FERMENTING MICROMONOSPORA INYOENSIS | SCHERING CORPORATION (US) | 1977-09-20 | — | — | US | claimed |
| US-4169141-A | 1-Peptidyl derivatives of di-O-aminoglycosyl-1,3-diaminocyclitol antibacterial agents | SHERING CORPORATION (US) | 1979-09-25 | — | — | US | disclosed |
| US-4049498-A | FERMENTING MICROMONOSPORA INYOENSIS | SCHERING CORPORATION (US) | 1977-09-20 | — | — | US | disclosed |
| US-4011390-A | SEMI-SYNTHETIC AMINOCYCLITOL AMINOGLYCOSIDE ANTIBIOTICS AND METHODS FOR THE PREPARATION THEREOF | SCHERING-PLOUGH CORPORATION (US) | 1977-03-08 | — | — | US | disclosed |