Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569298 | 0.98 | HTT (0.43) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL11569164 | 0.98 | HTT (0.43) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL28225664 | 0.83 | MEN1 (0.50) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL9717336 | 0.81 | MEN1 (0.54) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL11255913 | 0.80 | — | — | |
| SCHEMBL7572259 | 0.78 | — | — | |
| SCHEMBL11658732 | 0.78 | PTPN7 (0.48) | TSHRMEN1THRBKMT2AMAPT | |
| SCHEMBL8551377 | 0.78 | PTPN7 (0.48) | TSHRMEN1THRBKMT2AMAPT | |
| SCHEMBL8030954 | 0.78 | PTPN7 (0.48) | TSHRMEN1THRBKMT2AMAPT | |
| SCHEMBL9732267 | 0.78 | PTPN7 (0.48) | TSHRMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175201-A | Chemical synthesis | UNIVERSITY OF CHICAGO (US) | 1979-11-20 | — | — | US | disclosed |
| US-4018820-A | Chemical synthesis | THE UNIVERSITY OF CHICAGO (US) | 1977-04-19 | — | — | US | disclosed |