Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156704 | 0.89 | BRAF (0.42) | BRAFBDKRB1ALDH1A1KDM4ERIPK1 | |
| SCHEMBL2410003 | 0.85 | HTR2C (0.34) | BDKRB1HTR2CSLC6A4ALDH1A1KDM4E | |
| SCHEMBL1156870 | 0.83 | BRAF (0.41) | BRAFALDH1A1KDM4EKDM2BHTT | |
| SCHEMBL1156741 | 0.83 | FNTA (0.39) | ALDH1A1NR1H2 | |
| SCHEMBL1278700 | 0.82 | FNTA (0.39) | HTR2CSLC6A4ALDH1A1RIPK1 | |
| SCHEMBL1156915 | 0.82 | NAMPT (0.35) | HTR2CSLC6A4RIPK1GPR119ABHD6 | |
| SCHEMBL1156544 | 0.82 | HTR2C (0.37) | BDKRB1HTR2CSLC6A4ALDH1A1KDM4E | |
| SCHEMBL1278457 | 0.80 | FNTA (0.33) | HTR2CSLC6A4ALDH1A1KDM4ERIPK1 | |
| Hydrochloric Acid SCHEMBL4417841 | 0.80 | NSD2 (0.32) | BDKRB1HTR2CSLC6A4NR1H2CTSL | |
| SCHEMBL1157223 | 0.80 | BRAF (0.44) | BRAFALDH1A1KDM4EHTTKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048909-B2 | Proton pump inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-11-01 | — | — | US | disclosed |
| EP-2336107-A2 | Proton pump inhibitors | Takeda Pharmaceutical Company Limited (JP) | 2011-06-22 | — | — | EP | disclosed |
| US-20110028476-A1 | PROTON PUMP INHIBITORS | KAJINO MASAHIRO | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028476-A1 | PROTON PUMP INHIBITORS | HRH2, HRH4, CYP2C19 | BRAF 2101/4885BDKRB1 1315/4885HTR2C 924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.