Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | NPY1R | P25929 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | NPY2R | P49146 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | METAP2 | P50579 | 1/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025899 | 0.90 | KMT2A (0.74) | POLBKDM4EMAPTNPC1NPSR1 | |
| SCHEMBL30081452 | 0.90 | KMT2A (0.74) | POLBKDM4EMAPTNPC1NPSR1 | |
| SCHEMBL29528138 | 0.90 | KMT2A (0.74) | POLBKDM4EMAPTNPC1NPSR1 | |
| 1-Naphthol SCHEMBL28423286 | 0.83 | MEN1 (0.64) | POLBKDM4EMAPTNPC1NPSR1 | |
| SCHEMBL11679799 | 0.81 | NPC1 (0.74) | POLBKDM4EMAPTNPC1NPSR1 | |
| SCHEMBL12368184 | 0.80 | KMT2A (0.80) | POLBKDM4EMAPTNPC1NPSR1 | |
| SCHEMBL25016350 | 0.80 | POLB (1.00) | POLBKDM4EMAPTNPC1NPSR1 | |
| SCHEMBL5319772 | 0.80 | POLB (1.00) | POLBKDM4EMAPTNPC1NPSR1 | |
| SCHEMBL30260627 | 0.80 | POLB (1.00) | POLBKDM4EMAPTNPC1NPSR1 | |
| SCHEMBL30081453 | 0.80 | POLB (1.00) | POLBKDM4EMAPTNPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143034-A | LIGHTFAST | STERLING DRUG INC. (US) | 1979-03-06 | — | — | US | disclosed |