SCHEMBL11569817

SCHEMBL11569817

CCCCC[C@]12CCCC[C@H]1CNCC2

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 2/20 0.35
SLC6A3 Q01959 2/20 0.35
CCR2 P41597 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1073590 1.00 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3CCR2
SCHEMBL1073591 1.00 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3CCR2
SCHEMBL11287172 0.95 GAA (0.30) SLC6A2SLC6A4SLC6A3
SCHEMBL11576962 0.89 GAA (0.30) SLC6A2SLC6A4SLC6A3
SCHEMBL11577452 0.89 GAA (0.30) SLC6A2SLC6A4SLC6A3
SCHEMBL11784129 0.86 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3
SCHEMBL11791349 0.86 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3
SCHEMBL8861264 0.81 CYP1A2 (0.39)
SCHEMBL21462929 0.81 CYP1A2 (0.39)
SCHEMBL22996132 0.80 GAA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4150135-A ANALGESICS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-04-17 US disclosed
US-4150135-A ANALGESICS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-04-17 US disclosed