Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787675 | 0.78 | SLC7A5 (0.35) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7269855 | 0.78 | SLC7A5 (0.41) | CTSLCTSBCTSSCTSK | |
| SCHEMBL27492980 | 0.75 | AAK1 (0.39) | CTSLCTSBCTSSCTSKAAK1 | |
| SCHEMBL3045850 | 0.73 | DPP4 (0.45) | DPP4 | |
| SCHEMBL3045853 | 0.73 | DPP4 (0.45) | DPP4 | |
| SCHEMBL7346109 | 0.73 | SLC7A5 (0.38) | DPP4 | |
| SCHEMBL18277721 | 0.71 | SLC7A5 (0.34) | DPP4 | |
| SCHEMBL27766846 | 0.71 | AAK1 (0.34) | AAK1 | |
| SCHEMBL6295278 | 0.71 | DPP4 (0.36) | DPP4CA1CA2CA7 | |
| SCHEMBL26108601 | 0.68 | GSR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |