Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569703 | 1.00 | NR1I2 (0.42) | NR1I2FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL11570661 | 0.90 | NR1I2 (0.41) | NR1I2FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL11569706 | 0.90 | NR1I2 (0.41) | NR1I2FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL1840054 | 0.86 | NPC1 (0.48) | PRSS1PRSS2PRSS3ALDH1A1LMNA | |
| SCHEMBL1837682 | 0.86 | NPC1 (0.48) | PRSS1PRSS2PRSS3ALDH1A1LMNA | |
| SCHEMBL1833894 | 0.86 | NPC1 (0.48) | PRSS1PRSS2PRSS3ALDH1A1LMNA | |
| SCHEMBL1840465 | 0.84 | SMN1; SMN2 (0.47) | PRSS1PRSS2PRSS3ALDH1A1LMNA | |
| SCHEMBL1835289 | 0.80 | NPC1 (0.51) | PRSS1PRSS2PRSS3ALDH1A1LMNA | |
| SCHEMBL1838539 | 0.80 | NPC1 (0.54) | ALDH1A1LMNATSHRNPC1RAB9A | |
| SCHEMBL1842492 | 0.80 | NPC1 (0.51) | PRSS1PRSS2PRSS3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022814-A | Iodine containing organic carbonates for use as radiographic agents | LAFAYETTE PHARMACAL, INC. (US) | 1977-05-10 | — | — | US | claimed |
| US-4175544-A | X-RAYS OF BODY FOR MEDICAL DIAGNOSIS | Lafayette Pharmacal Inc. (US) | 1979-11-27 | — | — | US | disclosed |
| US-4022814-A | Iodine containing organic carbonates for use as radiographic agents | LAFAYETTE PHARMACAL, INC. (US) | 1977-05-10 | — | — | US | disclosed |