SCHEMBL1157271

SCHEMBL1157271

O=P(O)(O)OCCC=C(Cl)Cl

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 8/20 0.44
LPAR2 Q9HBW0 7/20 0.44
LPAR1 Q92633 5/20 0.40
MPI P34949 1/20 0.32
BTN3A1 O00481 1/20 0.31
TPI1 P60174 2/20 0.31
ENPP2 Q13822 1/20 0.31
PGK1 P00558 1/20 0.30
PGK2 P07205 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4564476 0.76 BTN3A1 (0.42) LPAR3LPAR2LPAR1MPIBTN3A1
SCHEMBL27042274 0.75 LPAR3 (0.57) LPAR3LPAR2LPAR1MPITPI1
SCHEMBL20530992 0.74 LPAR3 (0.47) LPAR3LPAR2LPAR1BTN3A1ENPP2
SCHEMBL4424102 0.73
SCHEMBL585242 0.71
SCHEMBL12478462 0.71
SCHEMBL721089 0.71 LPAR3 (0.41) LPAR3LPAR2LPAR1BTN3A1ENPP2
SCHEMBL831184 0.71 LPAR3 (0.41) LPAR3LPAR2LPAR1BTN3A1ENPP2
SCHEMBL811703 0.71 LPAR3 (0.55) LPAR3LPAR2LPAR1MPITPI1
SCHEMBL21612239 0.69 BTN3A1 (0.52) LPAR3LPAR2BTN3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7098172-B1 Prevention and treatment of lost circulation with crosslinked polymer material M-I L.L.C. (US) 2006-08-29 US claimed
US-4122046-A OF ACRYLAMIDE, METAL COMPLEX CATALYST MAXICHEM, INC., A CORP. OF NC 1978-10-24 US claimed
US-20110028356-A1 ANNULAR FLUIDS AND METHOD OF EMPLACING THE SAME M-I L.L.C. (US) 2011-02-03 US disclosed
US-7829509-B2 Annular fluids and method of emplacing the same M.I. L.L.C. (US) 2010-11-09 US disclosed
US-7098172-B1 Prevention and treatment of lost circulation with crosslinked polymer material M-I L.L.C. (US) 2006-08-29 US disclosed
US-20050176591-A1 Packer fluid; water-miscible solvent/viscosifying additive/curing agent/cross-linking inhibitor; for heavy oil production M-I L.L.C. (US) 2005-08-11 US disclosed
US-6908886-B2 Annular fluids and method of emplacing the same M-I L.L.C. (US) 2005-06-21 US disclosed
WO-2004063521-A2 ANNULAR FLUIDS AND METHODS OF EMPLACING THE SAME M-I L. L. C. (US) 2004-07-29 WO disclosed
US-20040138070-A1 Annular fluids and method of emplacing the same M-I L.L.C. 2004-07-15 US disclosed